The town of Pisco and its eponymous drink, are closely linked to the city of Ica. It’s a small enough town that residents do most of their shopping in Ica, only an hour away. The more important link is that the grapes used to make Pisco are mostly grown in Ica.
The town has few attractions besides the beach and port. It’s as good as Paracas as a base for visiting the Islas Ballestas and Paracas National Reserve.
Pisco is 3 hours drive south of Lima, just south of Chincha & north of Paracas. There are no major nearby airports but there is a small airport in Pisco. Capitán FAP Renán Elías Olivera Airport was built for the military but does have a few civilian flights. I recommend driving.